Ancestral Sequence Reconstruction PDF
By:David A Liberles
Published on 2007-05-31 by OUP Oxford
Ancestral sequence reconstruction is a technique of growing importance in molecular evolutionary biology and comparative genomics. As a powerful tool for testing evolutionary and ecological hypotheses, as well as uncovering the link between sequence and molecular phenotype, there are potential applications in a range of fields. Ancestral Sequence Reconstruction starts with a historical overview of the field, before discussing the potential applications in drug discovery and the pharmaceutical industry. This is followed by a section on computational methodology, which provides a detailed discussion of the available methods for reconstructing ancestral sequences (including their advantages, disadvantages, and potential pitfalls). Purely computational applications of the technique are then covered, including whole proteome reconstruction. Further chapters provide a detailed discussion on taking computationally reconstructed sequences and synthesizing them in the laboratory. The book concludes with a description of the scientific questions where experimental ancestral sequence reconstruction has been utilized to provide insights and inform future research. This research level text provides a first synthesis of the theories, methodologies and applications associated with ancestral sequence recognition, while simultaneously addressing many of the hot topics in the field. It will be of interest and use to both graduate students and researchers in the fields of molecular biology, molecular evolution, and evolutionary bioinformatics.
This Book was ranked at 13 by Google Books for keyword comparative education theory.
Book ID of Ancestral Sequence Reconstruction's Books is yCaQDwAAQBAJ, Book which was written byDavid A Liberleshave ETAG "cmwoQFIOeEw"
Book which was published by OUP Oxford since 2007-05-31 have ISBNs, ISBN 13 Code is 9780191538414 and ISBN 10 Code is 0191538418
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